Post-sequencing archiving of DNA samples can meet the current research and health needs of genomics and anticipate future technological developments. It offers the possibility of:
- Be able to return to the original sample used for bank preparation or direct resequencing
- It is commonly accepted that there are errors in genetic annotations. These are repeated from one genome to another, as the medieval copyist monks propagated errors from one manuscript to another. The work of correcting these errors will be extremely long and tedious and will require the return to the original samples. (Jean Weissenbach)
- In the future, the rapid and constant evolution of digital data formats will make this data difficult or even impossible to exploit.
- Keep sequencing intermediates or DNA libraries
- In sequencing processes, the intermediate data quickly saturates the servers but they are necessary to correct errors or to deepen certain points. Retaining the starting DNA or the banks avoids digital clutter, provided that the physical storage of biological samples does not lead to the alteration of the molecules.
This condition is fulfilled by the Imagene solution which guarantees the stability of the sample and thus ensures the maintenance of its quality and integrity with unalterable traceability. It brings to a gain on several levels
- possible return to the library
- saving storage space for digital data.
- no re-sampling of the patient with all the risks involved at each step and resampling is not always possible.